Cleaved Ycf1p Dimer in the IFwide-beta conformation
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
To Be Published
- Phosphatidylethanolamine (734 Da, Ligand)
- Unknown peptide (1 kDa, Protein from Saccharomyces cerevisiae)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- (1r)-2-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12e)-hexadeca-9,12-dienoate (673 Da, Ligand)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
- Cleaved ycf1p ifwide-beta dimer (Complex from Saccharomyces cerevisiae)
Cleaved Ycf1p Monomer in the Beta Conformation
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
To Be Published
- Unknown peptide from ycf1p r region (1 kDa, Protein from Saccharomyces cerevisiae)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cleaved ycf1p ifwide-beta monomer (Complex from Saccharomyces cerevisiae)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
Cleaved Ycf1p Monomer in the IFwide-alpha conformation
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
To Be Published
- Cleaved ycf1p ifwide-alpha monomer (Complex)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
- Unknown peptide from ycf1p r region (1 kDa, Protein from Saccharomyces cerevisiae)
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate (691 Da, Ligand)
Structure and dynamics of a pentameric KCTD5/Cullin3/GBeta1Gamma2 E3 ubiquitin ligase complex
Nguyen DM, Rath DH, Devost D, Pétrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hébert TE, Privé GG
Proc Natl Acad Sci U S A (2024) 121 [ DOI: 10.1073/pnas.2315018121 Pubmed: 38625940 ]
Image sets:
- MotionCorrected Data for K5C3Gbg Grid2 TILT
- K5C3Gbg1 Krios Data Grid 2 multiframe micrographs
- K5C3Gbg Particles
- K5C3Gbg Krios Data Grid 2 TILT multiframe micrographs. Collected with 40 degree tilt.
- K5C3Gbg1 Krios Data Grid 1 multiframe micrographs
- MotionCorrected Data for normal(Grid1+Grid2) K5C3Gbg
KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinement of KCTD5(CTD)/Gbeta1gamma2
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]
- Gbg2_human (Protein from Homo sapiens)
- Complex of substrate adaptor kctd5 with cullin-3 and substrate gbeta-gamma (Complex from Homo sapiens)
- Kctd5_human (Protein from Homo sapiens)
- Gbb1_human (Protein from Homo sapiens)
KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinement of KCTD5(BTB)/Cullin3(NTD)
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]
KCTD5/Cullin3/Gbeta1gamma2 Complex State A: Composite Map from RELION Multi-body Refinement
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 8u81
Q-score: 0.228
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]
- Cullin3 1-381 (Protein from Homo sapiens)
- Complex of substrate adaptor kctd5 with cullin-3 and substrate gbeta-gamma (Complex from Homo sapiens)
- Kctd5_human (Protein from Homo sapiens)
- Gbg2_human (Protein from Homo sapiens)
- Gbb1_human (Protein from Homo sapiens)
KCTD5/Cullin3/Gbeta1gamma2 Complex State A: Reference Map for Composite Map EMD-41996
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]
- Cullin3 1-381 (Protein from Homo sapiens)
- Kctd5 (Protein from Homo sapiens)
- Complex of substrate adaptor kctd5 with cullin-3 and substrate gbeta-gamma (Complex from Homo sapiens)
- Gbg2_human (Protein from Homo sapiens)
- Gbb1_human (Protein from Homo sapiens)
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]
Nguyen DM, Rath DH, Devost D, Petrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hebert TE, Prive GG
PNAS (2024) 121 pp. e2315018121-e2315018121 [ Pubmed: 38625940 DOI: doi:10.1073/pnas.2315018121 ]